Monkeypox is a rare, viral infection that does not usually cause serious illness. However, it can result in hospitalization or death.  

Get Protected, Get Vaccinated.
Madison County Health Department has a limited supply of JYNNEOS vaccine available for the prevention of monkeypox and smallpox.
Offering JYNNEOS Monkeypox vaccine

If you are eligible for the vaccine based on current state criteria, call us at 315-366-2361 - option 2 for a monkeypox vaccine appointment and options in Madison County.
Our clinics are open to out of county residents.

Click here for a list of upcoming Madison County clinics! (PDF) or > Find more clinics here

Limited supplies of the vaccine may be available in other Central New York counties. Click here to check for clinics in other counties OR Contact the Health Department in a nearby county to inquire about other opportunities to get the vaccine, no matter county you live in.

The primary vaccine being used during this outbreak in the U.S., licensed by the U.S. Food and Drug Administration (FDA) is the JYNNEOS Vaccine. This vaccine is a two-dose series, generally given 28 days apart, for the prevention of monkeypox among adults ages 18 years and older. You are considered fully vaccinated two weeks after your second dose. People who get vaccinated should continue to take steps to protect themselves from infection by avoiding close, skin-to-skin contact, including intimate contact, with someone who has monkeypox. 

  • CDC is currently working on studies to learn more about the JYNNEOS vaccine’s effectiveness for this outbreak to make any future vaccine recommendations, including whether booster shots may be needed. Learn more about how vaccines work.

Who is currently eligible for the Monkeypox vaccine in New York State?

Statewide eligibility currently includes the following New Yorkers:

  • Individuals with recent exposure to a suspected or confirmed monkeypox case within the past 14 days.
  • Those at high risk of a recent exposure to monkeypox, including gay men and members of the bisexual, transgender, and gender non-conforming community and other communities of men who have sex with men and who have engaged in intimate or skin-to-skin contact with others in the past 14 days areas where monkeypox is spreading.
  • Individuals who have had skin-to-skin contact with someone in a social network experiencing monkeypox activity, including men who have sex with men who meet partners through an online website, digital application ("app"), or social event, such as a bar or party.
  • Any individual that may be at risk of future exposure to infection with monkeypox, even though they are not at high risk of a recent exposure to monkeypox.

Check here for updates to eligibility.

Why are health officials concerned?

Monkeypox is spreading, and cases of monkeypox are presenting, in ways not typically seen in past monkeypox outbreaks. Although the current strain of monkeypox that is circulating in the U.S. is rarely fatal, symptoms can be extremely painful, and people might have permanent scarring resulting from the rash.

Where are cases of Monkeypox occurring?

What should I do if I was exposed or have symptoms consistent with monkeypox?

Contact your health care provider for a risk assessment, even if you don’t think you had contact with someone who has monkeypox. 

Who should be tested for Monkeypox?

People who think they have monkeypox or have had close personal contact with someone who has monkeypox should visit a healthcare provider to help them decide if they need to be tested for monkeypox.

What treatments may be available?

  • Antiviral medications exist to treat monkeypox, which may be appropriate for some people. 
  • Vaccines exist that can help reduce the chance and severity of infection in those who have been exposed.

New Yorkers who experience a painful rash or skin lesion should contact a healthcare provider about medication to help with pain management. Prescription medicated mouthwashes and topical gels can provide pain relief and keep rashes and lesions clean, and are widely available.

Guidance, Resources, and Information for Healthcare Providers

Downloadable materials from NYSDOH:

CDC Information and Resources